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The study found no difference in GERD symptom control, PPI dose escalation rates, or glycemic outcomes compared to patients on GLP-1 agonists without PPIs

The STEP 4 trial demonstrated this directly participants who switched to placebo after 20 weeks of semaglutide regained weight, while those who continued maintained their loss (Rubino et al., 2021)

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2019 May-Aug;27(2):2309499019842424

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In addition, an endometrial AO assembloid model was used in a floating, suspension co-culture system with blastoids and was found to mimic embryo implantation [87]